Author/Authors :
Gai، نويسنده , , Xinjie and Grigg، نويسنده , , Ronald and Khamnaen، نويسنده , , Tossapol and Rajviroongit، نويسنده , , Shuleewan and Sridharan، نويسنده , , Visuvanathar and Zhang، نويسنده , , Lixin and Collard، نويسنده , , Simon and Keep، نويسنده , , Ann، نويسنده ,
Abstract :
A novel palladium-catalysed three component cascade process is described involving carbonylation of an aryl iodide to generate an acyl palladium species which is intercepted by a primary aliphatic/aromatic amine, amide or sulfonamide followed by intramolecular Michael addition to afford 3-substituted isoindolin-1-ones in good yield.
