Title of article
Synthesis of 3-substituted isoindolin-1-ones via a palladium-catalysed 3-component carbonylation/amination/Michael addition process
Author/Authors
Gai، نويسنده , , Xinjie and Grigg، نويسنده , , Ronald and Khamnaen، نويسنده , , Tossapol and Rajviroongit، نويسنده , , Shuleewan and Sridharan، نويسنده , , Visuvanathar and Zhang، نويسنده , , Lixin and Collard، نويسنده , , Simon and Keep، نويسنده , , Ann، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
7441
To page
7443
Abstract
A novel palladium-catalysed three component cascade process is described involving carbonylation of an aryl iodide to generate an acyl palladium species which is intercepted by a primary aliphatic/aromatic amine, amide or sulfonamide followed by intramolecular Michael addition to afford 3-substituted isoindolin-1-ones in good yield.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654826
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