Author/Authors :
Lee، نويسنده , , Jeng-Lin and Lin، نويسنده , , Chi-Fong and Hsieh، نويسنده , , Ling-Yu and Lin، نويسنده , , Wan-Ru and Chiu، نويسنده , , Huey-Fen and Wu، نويسنده , , Yang-Chang and Wang، نويسنده , , Kun-Sheng and Wu، نويسنده , , Ming-Jung، نويسنده ,
Abstract :
Synthesis of 4-deoxy rollicosin analog 2 was completed in nine steps, which was based on palladium-catalyzed coupling of two building blocks 3 and 4. Lactone 3 was synthesized from 5-hexyn-1-ol, and vinyl iodide 4 was accessed from l-glutamate and 1-hexyne.