Author/Authors :
Nathalie Defacqz، نويسنده , , Nathalie and Tran-Trieu، نويسنده , , Van and Cordi، نويسنده , , Alex and Marchand-Brynaert، نويسنده , , Jacqueline، نويسنده ,
Abstract :
5-(Hydroxymethyl)-3-(t-butyloxycarbonyl)imidazoline 2 was prepared in four steps from 2,3-diaminopropionic acid in 72% overall yield. Mitsunobu reaction with a series of phenol derivatives gave the corresponding 5-(aryloxymethyl)-3-(t-butyloxycarbonyl)imidazolines 8a–l. Phthalimide and N-benzyl trifluoroacetamide also reacted.
