Title of article
Noviose mimics of the coumarin inhibitors of gyrase B
Author/Authors
Musicki، نويسنده , , Branislav and Periers، نويسنده , , Anne-Marie and Piombo، نويسنده , , Laurent and Laurin، نويسنده , , Patrick and Klich، نويسنده , , Michel and Dupuis-Hamelin، نويسنده , , Claudine and Lassaigne، نويسنده , , Patrice and Bonnefoy، نويسنده , , Alain، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
9259
To page
9262
Abstract
The design, synthesis, and biological activity in vitro of modified coumarin inhibitors of gyrase B are presented. Noviose, the sugar portion of coumarin antibiotics, was replaced by simplified mimics, a 5′,5′-dimethylcyclohexane or piperidine.
Keywords
antibiotics , Coumarin , Noviose , Structure–activity
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1656055
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