Title of article
Regioisomers in Vorbrüggenʹs guanine nucleoside synthesis; N9 selectivity with a glucosamine derivative and 2-N-acetyl-6-O-diphenylcarbamoylguanine
Author/Authors
Zhong، نويسنده , , Minghong and Robins، نويسنده , , Morris J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
9327
To page
9330
Abstract
Vorbrüggen coupling of trimethylsilylated 2-N-acetylguanine with pentofuranose derivatives gives N7/N9 glycosyl mixtures. The N9 isomers can be obtained selectively with 2-N-acetyl-6-O-diphenylcarbamoylguanine, and even with a less reactive glucosamine derivative.
Keywords
glucosylamine–guanine nucleoside , guanine N9/N7 selectivity , Vorbrüggen coupling
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1656101
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