Title of article :
Brevetoxin B5, a new brevetoxin analog isolated from cockle Austrovenus stutchburyi in New Zealand, the marker for monitoring shellfish neurotoxicity
Author/Authors :
Ishida، نويسنده , , Hitoshi and Nozawa، نويسنده , , Akira and Hamano، نويسنده , , Hiromitsu and Naoki، نويسنده , , Hideo and Fujita، نويسنده , , Tsuyoshi and Kaspar، نويسنده , , Heinrich F. and Tsuji، نويسنده , , Kuniro Tsuji، نويسنده ,
Abstract :
A new brevetoxin analog, brevetoxin B5 (BTX-B5) was isolated together with BTX-B1 and PbTx-3 from the New Zealand cockle Austrovenus stutchburyi harvested at an outbreak of neurotoxic shellfish poisoning early in 1993. The structure was elucidated by comparison of its spectral data (NMR and CAD FAB MS/MS) with those of BTX-B1 and PbTx-2, and confirmed by synthesis from PbTx-2 with SeO2 and H2O2. It was detected in the toxic greenshell mussel Perna canaliculus and Pacific oyster Crassostrea gigas collected at the same time.
Keywords :
NSP , New Zealand , Brevetoxin , BTX-B5
