Title of article :
Mixed sugar–nylon 14-, 28- and 42-membered ring macrocyclic lactams
Author/Authors :
Mayes، نويسنده , , Benjamin A. and Cowley، نويسنده , , Andrew R. and Ansell، نويسنده , , Christopher W.G. and Fleet، نويسنده , , George W.J. Fleet، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Hydrogenation of linear ω-azido-pentafluorophenyl esters from mixed oligomers of 6-amino-6-deoxy-d-galactonic acid (or 6-amino-6-deoxy-d-mannonic acid) and 6-aminohexanoic acid gives cyclic peptides containing 14-, 28- and 42-membered ring lactams. Hydrogenation of a tetrameric peptide derived from ε-amino acids gave a 28-membered ring lactam in 79% yield.
Keywords :
cyclic peptide , cyclodextrin , sugar amino acid , macrocyclic lactam , Biopolymer
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
