A novel reagent for the chemical phosphorylation of oligonucleotides
Author/Authors :
Michael Leuck، نويسنده , , Michael and Vagle، نويسنده , , Kurt E and Shawn Roach، نويسنده , , J and Wolter، نويسنده , , Andreas، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Pages :
4
From page :
321
To page :
324
Abstract :
A novel phosphoramidite reagent was developed to convert terminal hydroxyl groups of oligonucleotides into phosphate monoesters. The reagent’s appearance as a solid foam is advantageous for its manipulation and handling in solid-phase synthesis and improves its thermal stability.
