Title of article
Toward a synthesis of the antitumor macrolide peloruside A: a chiral pool approach for the C(1)–C(11) segment
Author/Authors
Gurjar، نويسنده , , Mukund K. and Pedduri، نويسنده , , Yakambram and Ramana، نويسنده , , C.V. and Puranik، نويسنده , , Vedavati G. and Gonnade، نويسنده , , Rajesh G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
387
To page
390
Abstract
Dihydroxylation of the glucose derived α,β-unsaturated lactones 6 and 13 was found to be on the α-face of the pyranolactone ring exclusively. The resulting dihydroxylated compound from 13 has been used in a synthesis of the lactone 4, which corresponds to C(1)–C(11) of peloruside A.
Keywords
Ring closing metathesis , Barton–McCombie deoxygenation , Mitsunobu reaction , Barbies reaction , Dess–Martin periodinane , dihydroxylation
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656411
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