Author/Authors :
Hioki، نويسنده , , Hideaki and Ohnishi، نويسنده , , Yumiko and Kubo، نويسنده , , Miwa and Nashimoto، نويسنده , , Emi and Kinoshita، نويسنده , , Yukinori and Samejima، نويسنده , , Miho and Kodama، نويسنده , , Mitsuaki، نويسنده ,
Abstract :
A fluorescence-labeled calix[4]arene library substituted with peptides at the upper rim was synthesized. Screening of the library for binding a dye-labeled oligopeptide indicated that some peptidocalix[4]arenes selectively bind the oligopeptide. The chemosensitivity of the library members for a target peptide was also investigated.
Keywords :
combinatorial library , binding assay , Calixarenes , Chemosensors