Title of article
Deprotection of a primary Boc group under basic conditions
Author/Authors
Tom ، نويسنده , , Norma J. and Simon، نويسنده , , Wendy M. and Frost، نويسنده , , Heather N. and Ewing، نويسنده , , Marcus، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
2
From page
905
To page
906
Abstract
Treatment of a primary t-butyl carbamate (Boc) group with excess sodium t-butoxide in slightly wet tetrahydrofuran or 2-methyltetrahydrofuran provides the corresponding primary amine in excellent yield. We believe the reaction proceeds through an isocyanate intermediate.
Keywords
Boc , Amine , t-butyl carbamate , Sodium t-butoxide , Isocyanate
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656750
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