Title of article :
Synthesis of (±)-pyranonaphthoquinone derivatives, a Cdc25A phosphatase inhibitor
Author/Authors :
Akiko Shimbashi، نويسنده , , Akiko and Ishikawa، نويسنده , , Yuichi and Nishiyama، نويسنده , , Shigeru، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
The novel pyranonaphthoquinone 2, carrying Cdc25A phosphatase inhibitory activity, has been successfully synthesized through tricyclic compound 16, which was obtained from 15 by using the intramolecular Michael addition. The precursor 9 was derived from 5-bromoveratraldehyde.
Keywords :
Cdc25A phophatase inhibitor , Pyranonaphthoquinone , Intramolecular Michael reaction , Cell cycle progression
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
