Author/Authors :
De Matteis، نويسنده , , Valeria and van Delft، نويسنده , , Floris L. and de Gelder، نويسنده , , René and Tiebes، نويسنده , , Jِrg and Rutjes، نويسنده , , Floris P.J.T.، نويسنده ,
Abstract :
Ring-closing metathesis (RCM) has been shown to be a viable tool to incorporate fluoride and trifluoromethyl substituents in (hetero)cyclic ring systems. 2-Fluoroacrylamides were cyclized to the corresponding lactams, and trifluoromethyl-substituted olefins were cyclized to yield trifluoromethylated cyclopentenes, pyrrolines and a dihydrofuran derivative.
