Author/Authors :
Hioki، نويسنده , , Hideaki and Kinami، نويسنده , , Hiroyuki and Yoshida، نويسنده , , Atsushi and Kojima، نويسنده , , Aoi and Kodama، نويسنده , , Mitsuaki and Takaoka، نويسنده , , Shigeru and Ueda، نويسنده , , Keisuke and Katsu، نويسنده , , Takashi، نويسنده ,
Abstract :
N,N′,N″-Trisubstituted-cyclo-triglycines were synthesized. The major conformation of these compounds has C3 symmetry, and the carbonyl groups and substituents on the nitrogen are inclined in the same direction. Their response to various metal ions was estimated by constructing ion-selective electrodes. Two of them responded selectively to Ca2+ over other cations, demonstrating that N,N′,N″-trisubstituted-cyclo-triglycines provide a new scaffold to act as host molecules.