Title of article
Solid-phase approach towards the synthesis of functionalized imidazo[1,2-b]pyrazol-2-ones
Author/Authors
Blass، نويسنده , , Benjamin E. and Srivastava، نويسنده , , Anil and Coburn، نويسنده , , Keith R. and Faulkner، نويسنده , , Amy L. and Janusz، نويسنده , , John J. and Ridgeway، نويسنده , , James M. and Seibel، نويسنده , , William L.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
1275
To page
1277
Abstract
The solid-phase synthesis of a series of imidazo[1,2-b]pyrazol-2-ones, an interesting 5,5-fused ring system, based on diverse set of hydrazine acids and malanonitriles is described. The method involves formation of 5-aminopyrazoles on solid support and subsequent cyclizative cleavage off the resin. Compounds were obtained in acceptable to excellent yields and are suitable for biological evaluation without further purification.
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657009
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