Title of article
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimethylamino-2-methylpentan-3-one
Author/Authors
Azzolina، نويسنده , , Ornella and Collina، نويسنده , , Simona and Brusotti، نويسنده , , Gloria and Rossi، نويسنده , , Daniela and Linati، نويسنده , , Laura and Lanza، نويسنده , , Enrica and Ghislandi، نويسنده , , Victor، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
1355
To page
1357
Abstract
The diastereoselective synthesis of naphthyl amino alcohols via nucleophilic addition to racemic 1-dimethylamino-2-methylpentan-3-one was studied. The use of the appropriate experimental conditions allowed the synthesis of both diastereoisomers. The relative configurations were established via NOESY experiments.
Keywords
diastereoselective synthesis , Chiral aryl amino alcohols , Relative configuration
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657053
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