Title of article :
A practical, solvent free, one-pot synthesis of C2-symmetrical secondary amines
Author/Authors :
Alexakis، نويسنده , , Alexandre and Gille، نويسنده , , Ségolène and Prian، نويسنده , , Fabrice and Rosset، نويسنده , , Stéphane and Ditrich، نويسنده , , Klaus، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
A novel one-pot reductive amination of ketones using the combination Ti(OiPr)4/H2/Pd–C is reported. This practical procedure does not require any solvent, and affords C2-symmetrical secondary amines in high yields and excellent diastereoselectivities.
Keywords :
Titanium isopropoxide , C2-symmetry , chiral amines , reductive amination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
