Title of article :
Applications of Baylis–Hillman acetates: one-pot, facile and convenient synthesis of substituted γ-lactams
Author/Authors :
Basavaiah، نويسنده , , Deevi and Srivardhana Rao، نويسنده , , Jamjanam، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
A simple, convenient and one-pot transformation of the acetates of Baylis–Hillman adducts into substituted γ-lactams, that is, (E)-5-alkyl-3-arylidenepyrrolidin-2-ones via treatment with nitroalkanes in the presence of a base, followed by reductive cyclization, using Fe/AcOH, is described.
Keywords :
Baylis–Hillman chemistry , ?-Lactams , reductive cyclization , Fe/AcOH
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
