Author/Authors :
Ohira، نويسنده , , Susumu and Fujiwara، نويسنده , , Hiroyuki and Maeda، نويسنده , , Kiyomi and Habara، نويسنده , , Masaharu and Sakaedani، نويسنده , , Naomi and Akiyama، نويسنده , , Megumi and Kuboki، نويسنده , , Atsuhito، نويسنده ,
Abstract :
All diastereomers of pentenocin B, an inhibitor of interleukin-1β converting enzyme produced by Trichoderma hamatum FO-6903, were synthesized in chiral forms starting from l-threonine. Absolute configurations of natural pentenocin B were clarified to be 4S, 5R, and 6R.
Keywords :
Pentenocin , C–H insertion , alkylidenecarbene , L-threonine
