Title of article
Synthesis of 1-indanones by intramolecular Friedel–Crafts reaction of 3-arylpropionic acids catalyzed by Tb(OTf)
Author/Authors
Cui، نويسنده , , Dong-Mei and Zhang، نويسنده , , Chen and Kawamura، نويسنده , , Masato and Shimada، نويسنده , , Shigeru، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
1741
To page
1745
Abstract
Intramolecular Friedel–Crafts acylation reaction of 3-arylpropionic acids was efficiently catalyzed by Tb(OTf)3 at 250 °C to give 1-indanones. Even deactivated 3-arylpropionic acids with halogen atoms on the aromatic ring can be cyclized in moderation to good yields.
Keywords
indanone , Lewis acid , Friedel–Crafts reaction , dehydration , Lanthanoid , cyclization , acylation
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657265
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