Title of article :
Synthesis of 1-indanones by intramolecular Friedel–Crafts reaction of 3-arylpropionic acids catalyzed by Tb(OTf)
Author/Authors :
Cui، نويسنده , , Dong-Mei and Zhang، نويسنده , , Chen and Kawamura، نويسنده , , Masato and Shimada، نويسنده , , Shigeru، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Intramolecular Friedel–Crafts acylation reaction of 3-arylpropionic acids was efficiently catalyzed by Tb(OTf)3 at 250 °C to give 1-indanones. Even deactivated 3-arylpropionic acids with halogen atoms on the aromatic ring can be cyclized in moderation to good yields.
Keywords :
indanone , Lewis acid , Friedel–Crafts reaction , dehydration , Lanthanoid , cyclization , acylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
