Title of article :
On the paradox of TiCl4 reducing power: pinacol coupling and two-carbon homologation of carbonyl compounds
Author/Authors :
Clerici، نويسنده , , Angelo and Pastori، نويسنده , , Nadia and Porta، نويسنده , , Ombretta، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
TiCl4/DIPEA/CH2Cl2 reducing system promotes pinacol coupling and/or reduction to alcohol of aromatic aldehydes and carbonyl compounds activated towards reduction by an electron withdrawing group. In addition, bis homologation of these substrates is observed. An inner-sphere electron transfer from TiCl4 to DIPEA accounts for the products distribution.
Keywords :
Electron transfer , DIPEA , Pinacol coupling , Carbon homologation , Titanium tetrachloride
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
