Title of article
On the paradox of TiCl4 reducing power: pinacol coupling and two-carbon homologation of carbonyl compounds
Author/Authors
Clerici، نويسنده , , Angelo and Pastori، نويسنده , , Nadia and Porta، نويسنده , , Ombretta، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
1825
To page
1827
Abstract
TiCl4/DIPEA/CH2Cl2 reducing system promotes pinacol coupling and/or reduction to alcohol of aromatic aldehydes and carbonyl compounds activated towards reduction by an electron withdrawing group. In addition, bis homologation of these substrates is observed. An inner-sphere electron transfer from TiCl4 to DIPEA accounts for the products distribution.
Keywords
Electron transfer , DIPEA , Pinacol coupling , Carbon homologation , Titanium tetrachloride
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657299
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