Title of article
Synthesis of substituted quinolines by iron-catalyzed coupling reactions between chloroenynes and Grignard reagents
Author/Authors
Seck، نويسنده , , Matar and Franck، نويسنده , , Xavier and Hocquemiller، نويسنده , , Reynald and Figadère، نويسنده , , Bruno and Peyrat، نويسنده , , Jean-François and Provot، نويسنده , , Olivier and Brion، نويسنده , , Jean-Daniel and Alami، نويسنده , , Mouâd، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
1881
To page
1884
Abstract
This letter reports the preparation of quinolines, substituted at the 2- or 3-position by a 4-substituted but-3-en-1-yne group, by the environmentally friendly iron(III)-catalyzed coupling reaction of Grignard reagents with 1-chloro-4-(2-quinolyl)but-1-en-3-yne. The extension and the scope of this non-toxic and chemoselective procedure to various functionalized unsaturated vinyl chlorides are described.
Keywords
Anti-leishmania , Enynes , Vinyl chlorides , Quinolines , Iron , Grignard reagents
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657324
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