Title of article
First synthesis of (±)-bis-homosarkomycin ethyl ester
Author/Authors
Ali Samarat، نويسنده , , Ali and Landais، نويسنده , , Yannick and Amri، نويسنده , , Hassen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
2
From page
2049
To page
2050
Abstract
A five step synthesis of (±)-bis-homosarkomycin ethyl ester 6 has been achieved starting from commercially available ethyl phosphonoacetate and ethyl 5-bromovalerate. The successful synthetic approach to 6 uses α-methylene pimelate 3 as a key intermediate.
Keywords
Cyclisation , Horner–Wadsworth–Emmons reaction , Functional phosphonoacetate , Michael addition
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657409
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