Author/Authors :
Abe، نويسنده , , Hitoshi and Takeda، نويسنده , , Shigemitsu and Fujita، نويسنده , , Takuro and Nishioka، نويسنده , , Keisuke and Takeuchi، نويسنده , , Yasuo and Harayama، نويسنده , , Takashi، نويسنده ,
Abstract :
A Pd-mediated intramolecular aryl–aryl coupling reaction of phenyl benzoate derivatives were examined to form benzo[c]chromen-6-ones, and then enantioselective lactone-opening reaction with a borane–oxazaborolidine combination was carried out. The resulting biphenyl was transformed into a key intermediate for the stegane related compounds. The absolute configuration of the biphenyl is also discussed.
Keywords :
Steganone , Biaryl , Lactone concept , PALLADIUM , Phenyl benzoate
