Title of article
Tandem amine propargylation-Sonogashira reactions: new three-component coupling leading to functionalized substituted propargylic amines
Author/Authors
Olivi، نويسنده , , Nathanaël and Spruyt، نويسنده , , Philippe and Peyrat، نويسنده , , Jean-François and Alami، نويسنده , , Mouâd and Brion، نويسنده , , Jean-Daniel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
2607
To page
2610
Abstract
Three-component coupling reactions of propargyl halides, amines, and organic halides in the presence of palladium–copper catalysis produced efficiently highly functionalized propargylic amines in good to excellent yields at room temperature. Extension to the synthesis of 2-(dialkylaminomethyl)benzo[b]furan or indole derivatives is described.
Keywords
Sonogashira , Propargyl halides , Propargylic amines , PALLADIUM , 2-(Dialkylaminomethyl)indoles , 2-(Dialkylaminomethyl)benzofuranes
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657686
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