Title of article
A triazene-based new photolabile linker in solid phase chemistry
Author/Authors
Enders، نويسنده , , Dieter and Rijksen، نويسنده , , Christiaan and Bremus-Kِbberling، نويسنده , , Elke and Gillner، نويسنده , , Arnold and Kِbberling، نويسنده , , Johannes، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
2839
To page
2841
Abstract
An extension of the T2 linker methodology by showing its applicability as a photocleavable linker is reported. Photocleavage was carried out with 355 nm UV laser irradiation (3ω Nd-YAG) in methanol/diethyl ether and is suitable for protected amino acid derivatives, as well as simple small organic molecules including resin-bound biotin. The linker is stable under a wide range of conditions with the exception of strongly acidic media.
Keywords
Solid phase synthesis , photochemistry , cleavage , Triazene , Amino acid
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657803
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