Title of article :
An efficient synthesis of the orally-active GpIIb/IIIa antagonist FR184764
Author/Authors :
Yamanaka، نويسنده , , Toshio and Ohkubo، نويسنده , , Mitsuru and Takahashi، نويسنده , , Fumie and Kato، نويسنده , , Masayuki، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
An efficient synthesis of the orally-active GpIIb/IIIa antagonist FR184764 was achieved. The key intermediate, an optically active ethynyl β-amino ester, was synthesized efficiently by utilizing a lipase catalyzed kinetic resolution step.
Keywords :
Orally-active , Lipase catalyzed kinetic resolution , FR184764 , GpIIb/IIIa antagonist
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
