Title of article
An efficient synthesis of the orally-active GpIIb/IIIa antagonist FR184764
Author/Authors
Yamanaka، نويسنده , , Toshio and Ohkubo، نويسنده , , Mitsuru and Takahashi، نويسنده , , Fumie and Kato، نويسنده , , Masayuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
2843
To page
2845
Abstract
An efficient synthesis of the orally-active GpIIb/IIIa antagonist FR184764 was achieved. The key intermediate, an optically active ethynyl β-amino ester, was synthesized efficiently by utilizing a lipase catalyzed kinetic resolution step.
Keywords
Orally-active , Lipase catalyzed kinetic resolution , FR184764 , GpIIb/IIIa antagonist
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657805
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