Title of article
Simple and facile reduction of azides to amines: synthesis of DNA interactive pyrrolo[2,1-c][1,4]benzodiazepines
Author/Authors
Kamal، نويسنده , , Ahmed and Reddy، نويسنده , , P.S.M.M. and Reddy، نويسنده , , D.Rajasekhar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
6629
To page
6631
Abstract
The reduction of aromatic azido compounds to the corresponding amines with hydriodic acid has been investigated and found to result in high yields. This reductive methodology which proceeds under non refluxing condition has been extended for the synthesis of DNA-interactive pyrrolo[2,1-c][1,4] benzodiazepine antibiotics.
Keywords
Amines , reductive cyclization , Hydriodic acid , Pyrrolobenzodiazepines
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1657999
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