Title of article
Self-assembly of a tetrapeptide in which a unique supramolecular helical structure is formed via intermolecular hydrogen bonding in the solid state
Author/Authors
Maji، نويسنده , , Samir Kumar and Banerjee، نويسنده , , Arijit and Drew، نويسنده , , Michael G.B. and Haldar، نويسنده , , Debasish and Banerjee، نويسنده , , Arindam، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
6759
To page
6762
Abstract
A single crystal X-ray diffraction study of the tetrapeptide Boc-Ala1-Aib2-Leu3-Aib4-OMe 1 (Aib: α-aminoisobutyric acid) reveals that it forms a supramolecular helix through continuous intermolecular hydrogen bonds. Scanning electron microscopic studies show that this peptide exhibits amyloid-like fibrillar morphology in the solid state.
Keywords
supramolecular helix , AIB , amyloid fibrils , intermolecular hydrogen bonds
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658081
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