Title of article :
Synthesis of enediyne model compounds possessing a cyanohydrin moiety as a triggering device
Author/Authors :
Suzuki، نويسنده , , Ichiro and Tsuchiya، نويسنده , , Yuko and Shigenaga، نويسنده , , Akira and Nemoto، نويسنده , , Hisao and Shibuya، نويسنده , , Masayuki، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
3
From page :
6779
To page :
6781
Abstract :
Development of enediyne model compounds possessing a cyanohydrin moiety is described. These model compounds generate enyne–allenylketones efficiently under mild basic conditions and the resulting biradicals showed potent DNA cleaving abilities.
Keywords :
radicals , Ionization , cyanohydrins , DNA , diynes , Enynes
Journal title :
Tetrahedron Letters
Serial Year :
2002
Journal title :
Tetrahedron Letters
Record number :
1658094
Link To Document :
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