Title of article
Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin
Author/Authors
Park، نويسنده , , Hae-Ryong and Furihata، نويسنده , , Kazuo and Hayakawa، نويسنده , , Yoichi and Shin-ya، نويسنده , , Kazuo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
5
From page
6941
To page
6945
Abstract
We discovered a novel down-regulator of grp78 gene expression designated as versipelostatin from the culture broth of Streptomyces versipellis 4083-SVS6. Its structure was determined to be a macrocyclic compound consisting of an α-acyltetronic acid and sugar moieties.
Keywords
Macrocyclic , versipelostatin , ?-acyltetronic acid , GRP78 , Endoplasmic reticulum stress
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658176
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