Title of article :
Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin
Author/Authors :
Park، نويسنده , , Hae-Ryong and Furihata، نويسنده , , Kazuo and Hayakawa، نويسنده , , Yoichi and Shin-ya، نويسنده , , Kazuo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
We discovered a novel down-regulator of grp78 gene expression designated as versipelostatin from the culture broth of Streptomyces versipellis 4083-SVS6. Its structure was determined to be a macrocyclic compound consisting of an α-acyltetronic acid and sugar moieties.
Keywords :
Macrocyclic , versipelostatin , ?-acyltetronic acid , GRP78 , Endoplasmic reticulum stress
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters