A general method for the highly diastereoselective, kinetically controlled alkylation of (+)-nopinone
Author/Authors :
Campos، نويسنده , , Kevin Curran & James Lee، نويسنده , , Sandra and Journet، نويسنده , , Michel and Kowal، نويسنده , , Jason J and Cai، نويسنده , , Dongwei and Larsen، نويسنده , , Robert D and Reider، نويسنده , , Paul J، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
3
From page :
6957
To page :
6959
Abstract :
A general method for the monoalkylation of (+)-nopinone was developed for a variety of carbon and heteroatom electrophiles to afford the kinetically controlled product 2 with high diastereoselectivity (98% d.e.) and excellent yield (75–90%).
