Author/Authors :
Grimaud، نويسنده , , Laurence and Rotulo، نويسنده , , Delphine and Ros-Perez، نويسنده , , Rafael and Guitry-Azam، نويسنده , , Ludivine and Prunet، نويسنده , , Joëlle، نويسنده ,
Abstract :
A short route to sulfones 9a–c is described. These synthons encompassing a syn 1,3-diol motif are model compounds for the C16–C24 fragment of Dolabelides. The benzylidene protecting group can be reduced regioselectively to furnish β-hydroxysulfones 10a–b. First attempts of Julia coupling of the dianions derived from these substrates with aldehydes and ketones are also reported.
