Author/Authors :
Gomez، نويسنده , , Laurent and Ngouela، نويسنده , , Silvère and Gellibert، نويسنده , , Françoise and Wagner، نويسنده , , Alain and Mioskowski، نويسنده , , Charles، نويسنده ,
Abstract :
CPMA is an efficient agent for the formation of esters and amides from carboxylic acids. It is compatible with substrates that are sensitive to basic conditions or oxophilic reagents. The reaction proceeds without racemization of chirally labile carboxylic acids. All these advantages make CPMA a valuable adjunct to the existing arsenal of coupling reagents.
Keywords :
Amide bond , Coupling reagent , methylene ammonium salt , ester bond