Author/Authors :
Filippov، نويسنده , , Dmitri V. and van Zoelen، نويسنده , , Dirk J. and Oldfield، نويسنده , , Steven P. and van der Marel، نويسنده , , Gijs A. and Overkleeft، نويسنده , , Herman S. and Drijfhout، نويسنده , , Jan W. and van Boom، نويسنده , , Jacques H.، نويسنده ,
Abstract :
Three novel fluorous reagents (i.e. 1–3), derived from benzyl chloroformate (Z-Cl), have been synthesized and used for the tagging of peptides prepared following a Fmoc-based solid-phase approach. It is shown that the implementation of a benzyloxycarbonyl (Z)-based fluorophilic tag facilitates purification of peptides using fluorous reverse phase chromatography.
