• Title of article

    A one-flask synthesis of α,α-bisphosphonates via enolate chemistry

  • Author/Authors

    Du، نويسنده , , Yanming and Jung، نويسنده , , Kang-Yeoun and Wiemer، نويسنده , , David F.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    8665
  • To page
    8668
  • Abstract
    Treatment of several carbonyl compounds with excess strong base and diethyl phosphorochloridite results in formation of two carbonphosphorus bonds at the α carbon. Oxidation of the immediate product with H2O2 affords the corresponding α,α-bisphosphonate in moderate to very good yields.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1659200