• Title of article

    Preparation of 2-hydroxybenzamidines from 3-aminobenzisoxazoles

  • Author/Authors

    Lepore، نويسنده , , Salvatore D and Schacht، نويسنده , , Aaron L and Wiley، نويسنده , , Michael R، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    3
  • From page
    8777
  • To page
    8779
  • Abstract
    2-Hydroxybenzamidines have been prepared from 3-aminobenzisoxazoles by reductive cleavage of the nitrogen–oxygen bond using catalytic hydrogenation, Zn/AcOH or NiCl2/NaBH4. This ring-opening reaction can be accomplished chemoselectively in the presence of a variety of hydrogenation-sensitive functional groups including an aryl bromide, benzyl carbamate, and olefin.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1659265