Title of article
Room temperature dehalogenation of chloroarenes by polymethylhydrosiloxane (PMHS) under palladium catalysis
Author/Authors
Robert E. and Rahaim Jr.، نويسنده , , Ronald J. and Maleczka Jr.، نويسنده , , Robert E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
8823
To page
8826
Abstract
The first method for the reduction of chloroarenes by polymethylhydrosiloxane (PMHS) is reported. Catalytic amounts of palladium(II) acetate in combination with PMHS and aqueous KF will rapidly hydrodehalogenate aryl chlorides at room temperature. The mildness of the method is demonstrated by its tolerance of ketones, amides, esters, nitriles, ethers, borate esters, and amines.
Keywords
Hydrodehalogenation , chlorides , Reduction , PMHS , PALLADIUM
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659286
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