Author/Authors :
Marcantonio، نويسنده , , Karen M. and Frey، نويسنده , , Lisa F. and Murry، نويسنده , , Jerry A. and Chen، نويسنده , , Cheng-yi، نويسنده ,
Abstract :
This article describes a facile synthesis of 2-substituted-5-(ketoaryl)thiazoles, which are important intermediates for the synthesis of biologically active compounds. A variety of 2-substituted thiazole anions were added to aryl nitriles to provide the desired ketones after aqueous hydrolysis.
