Title of article :
Synthesis of substituted 1H-imidazol-1-ylmethylpiperidines. Facile separation of 1,4- and 1,5-disubstituted imidazoles
Author/Authors :
Rivera، نويسنده , , Jocelyn and Jayasuriya، نويسنده , , Nilukshi and Rane، نويسنده , , Dinanath and Keertikar، نويسنده , , K. and Ferreira، نويسنده , , J.Albert and Chao، نويسنده , , Jianping and Minor، نويسنده , , Keith and Guzi، نويسنده , , Timothy، نويسنده ,
Abstract :
The synthesis of several 1H-imidazol-1-ylmethylpiperidines is described. A method for the regioselective isolation of 1,4-disubstituted imidazoles utilizing the selective quaternization of the 1,5-disubstituted regioisomer was developed.
