Author/Authors :
Shoji، نويسنده , , Mitsuru and Kishida، نويسنده , , Satoshi and Takeda، نويسنده , , Mitsuhiro and Kakeya، نويسنده , , Hideaki and Osada، نويسنده , , HIROYUKI and HAYASHI، نويسنده , , Yujiro، نويسنده ,
Abstract :
A practical total synthesis of both enantiomers of epoxyquinols A and B has been developed. Key reactions are the chromatography-free preparation of an iodolactone by using acryloyl chloride as dienophile in the Diels–Alder reaction of furan, the lipase-mediated kinetic resolution of a cyclohexenol derivative, and a modified procedure for α-iodonation of a cyclohexenone.
Keywords :
Diels–Alder reaction , Lipase , epoxyquinols A and B , RESOLUTION
