Title of article
Copper-mediated reaction of 2-halopyridines with ethyl bromodifluoroacetate
Author/Authors
Ashwood، نويسنده , , Michael S. and Cottrell، نويسنده , , Ian F. and Cowden، نويسنده , , Cameron J. and Wallace، نويسنده , , Debra J. and Davies، نويسنده , , Antony J. and Kennedy، نويسنده , , Derek J. and Dolling، نويسنده , , Ulf H.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
9271
To page
9273
Abstract
A facile process for the preparation of substituted ethyl 2′-pyridyldifluoroacetates 3 is described starting from readily available ethyl bromodifluoroacetate 2 and substituted 2-bromo or 2-chloropyridines 1. This process features a copper-mediated cross-coupling reaction in DMSO and is the first to utilise pyridylbromides or chlorides with ethyl bromodifluoroacetate 2 in this reaction.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659560
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