A copper- and amine-free Sonogashira-type coupling procedure catalyzed by oxime palladacycles

Oxime palladacycle derived from 4,4′-dichlorobenzophenone was found to promote the Sonogashira reaction of aryl iodides and aryl bromides with terminal acetylenes using 1 equivalent of tetrabutylammonium acetate in organic solvents generally in 1 h at 110°C and in high TONs (up to 72000).