Title of article
New and efficient synthesis of 5′-amino-5′-(S)-methyl-2′,5′-dideoxynucleosides
Author/Authors
Jung، نويسنده , , Pierre M.J. and Beaudegnies، نويسنده , , Renaud and De Mesmaeker، نويسنده , , Alain and Wendeborn، نويسنده , , Sebastian، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
293
To page
297
Abstract
A short, efficient synthesis of 5′-amino-5′-(S)-methyl-2′,5′-dideoxynucleosides 1 has been developed through the diastereoselective addition of methylmagnesium bromide or methyllithium to an intermediate tert-butylsulfinimide.
Keywords
tert-butylsulfinamide , nucleophilic addition , 5?-amino-5?-(S)-methyl-2? , 5?-dideoxynucleosides
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1659986
Link To Document