Author/Authors :
Marcos ، نويسنده , , I.S and Pedrero، نويسنده , , A.B and Sexmero، نويسنده , , M.J and Diez، نويسنده , , D and Basabe، نويسنده , , P and Hernلndez، نويسنده , , F.A and Urones، نويسنده , , J.G، نويسنده ,
Abstract :
The first three natural ent-halimanolides known until now have been synthesized from ent-halimic acid. Their structure have been confirmed as well as their absolute configurations established. Bestmann methodology has been used for the synthesis of butenolides and for the γ-hydroxybutenolides synthesis the Boukouvalas method has been employed. Biological testing has been carried out on these compounds.