Title of article :
An unusual dehalogenation in the Suzuki coupling of 4-bromopyrrole-2-carboxylates
Author/Authors :
Handy، نويسنده , , Scott T and Bregman، نويسنده , , Howard and Lewis، نويسنده , , Jennifer and Zhang، نويسنده , , Xiaolei and Zhang، نويسنده , , Yanan، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
An unusual dehalogenation of 4-bromopyrrole-2-carboxylates under Suzuki coupling conditions has been observed. This dehalogenation can be suppressed by protection of the pyrrole nitrogen. Using a BOC protecting group, not only is dehalogenation suppressed, but the protecting group is also removed under the reaction conditions.
Keywords :
pyrroles , Protecting group , Suzuki coupling , Dehalogenation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
