Title of article
Synthesis of trimethylammoniumphenylthio-substituted phthalocyanines with different pattern of substitution
Author/Authors
Giuntini، نويسنده , , Francesca and Nistri، نويسنده , , Daniele and Chiti، نويسنده , , Giacomo and Fantetti، نويسنده , , Lia and Jori، نويسنده , , Giulio and Roncucci، نويسنده , , Gabrio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
515
To page
517
Abstract
The base-catalyzed cyclotetramerization of 3-, 4- and 4,5-dimethylaminophenylthio phthalonitriles with zinc(II)acetate afforded 1(4),8(11),15(18),22(25)- and 2(3),9(10),16(17),23(24)-tetrasubstituted and 2,3,9,10,16,17,23,24-octasubstituted Zn(II)phthalocyanines, respectively. The statistical mixed condensation of the same phthalonitriles with 1,2-dicyanobenzene gave the corresponding mono- and disubstituted derivatives. Methylation of such products afforded a series of cationic Zn(II)phthalocyanines with different pattern of substitution, with potential use as photodynamic agents in microbial infections.
Keywords
zinc(II)phthalocyanines , phthalonitriles , cationic photosensitizers , PDT
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1660116
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