Author/Authors :
Ayad، نويسنده , , Tahar and Génisson، نويسنده , , Yves and Verdu، نويسنده , , Alexandre and Baltas، نويسنده , , Michel and Gorrichon، نويسنده , , Liliane، نويسنده ,
Abstract :
The use of a trans α,β-epoxyaldehyde as a precursor of d-ribo-phytosphingosines was studied. The highly stereoselective alkylation of the aldehyde with a diorganozinc reagent was ensured through double asymmetric induction. The regioselective opening of the epoxide in turn gives access to an azide from which a C10 phytosphingosine can be easily prepared.
