Title of article :
Synthesis of the four diastereoisomers of 3-thymine-1-(tbutoxycarbonyl)aminocyclopentane-1-carboxylic acid
Author/Authors :
Howarth، نويسنده , , Nicola M. and Wakelin، نويسنده , , Laurence P.G. and Walker، نويسنده , , David M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Synthetic routes to all four diastereoisomers of 3-thymine-1-(tbutoxycarbonyl)aminocyclopentane-1-carboxylic acid have been developed starting from the commercially available (S)-dimethyl malate. The key step in the synthesis involves dialkylation of N-(diphenylmethylene)glycine ethyl ester with 1,4-diiodo-2(S)-trityloxybutane.
Keywords :
PNA , homoserine analogues , Cyclic ? , ?-disubstituted amino acids
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
