Title of article :
SYNPHOS®, a new chiral diphosphine ligand: synthesis, molecular modeling and application in asymmetric hydrogenation
Author/Authors :
Duprat de Paule، نويسنده , , Sébastien and Jeulin، نويسنده , , Séverine and Ratovelomanana-Vidal، نويسنده , , Virginie and Genêt، نويسنده , , Jean-Pierre and Champion، نويسنده , , Nicolas and Dellis، نويسنده , , Philippe، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
A new optically active diphosphine ligand, [(5,6),(5′,6′)-bis(ethylenedioxy)biphenyl-2,2′-diyl]bis(diphenylphosphine) (SYNPHOS®) has been synthesized and used in ruthenium-catalyzed asymmetric hydrogenation. This new ligand has been compared to other diphosphines (BINAP and MeO-BIPHEP), regarding their dihedral angles and the enantioselectivity in the ruthenium mediated hydrogenation reaction.
Keywords :
molecular modeling , Ruthenium , Diphosphine ligand , asymmetric hydrogenation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
